Jeremy Hill
Adjunct Professor/Scientist
Post-doc: Washington University in St Louis, USA
PhD: Temple University - Philadelphia, USA
B.A: University of Wisconsin - Madison, USA
Office: Robarts Research Institute, Room 7239
Phone: 646-319-2053
Email: jhill272@uwo.ca
Area of Study:
Innate immune regulation of neuroinflammation and synapse elimination during viral encephalitis.
Fields of Interest:
- Infectious Diseases
- Viral encephalitis
- Monocytes/Macrophages
- Cannabinoids
- NeuroImmune interactions
- Blood Brain Barrier breakdown
Research Profile
Dr. Hill’s research focuses on the complex interplay between the immune and central nervous systems during viral encephalitis. The goal is to elucidate underlying neuroimmune mechanisms triggered during acute viral infection which contribute to synapse loss and cognitive decline associated with Zika virus (ZIKV) induced encephalitis.
His research is primarily focused on how cells of the innate immune system, specifically peripherally derived monocytes, infiltrate the CNS and regulate hippocampal synapse elimination and promote an excessive neuroinflammatory milieu.
Using cutting-edge techniques in immunology, neurobiology, and molecular biology, Dr. Hill phenotypically modulates monocyte subsets to explore their contribution to neuroinflammation, elimination of synaptic connections, and the phagocytosis of both infected and healthy, bystander neural cells. Ultimately, his research aims to identify novel therapeutic strategies to mitigate and resolve prolonged neuroinflammatory conditions due to viral infection.
